ChemicalBook > CAS DataBase List > SUC-ALA-ALA-PRO-PHE-PNA

SUC-ALA-ALA-PRO-PHE-PNA

Product Name
SUC-ALA-ALA-PRO-PHE-PNA
CAS No.
70967-97-4
Chemical Name
SUC-ALA-ALA-PRO-PHE-PNA
Synonyms
SAAPNA;SUC-AAPF-PNA;Cathepsin G substrate;70967-97-4/107409-54-1;SUC-ALA-ALA-PRO-PHE-PNA;Cathepsin G Substrate I;N-SUCCINYL-ALA-ALA-PRO-PHE-PNA;SUC-ALA-ALA-PRO-PHE-PNA USP/EP/BP;SUC-ALA-ALA-PRO-PHE-PARANITROANILIDE;CATHEPSIN G SUBSTRATE I, COLORIMETRIC
CBNumber
CB9399626
Molecular Formula
C30H36N6O9
Formula Weight
624.64
MOL File
70967-97-4.mol
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SUC-ALA-ALA-PRO-PHE-PNA Property

storage temp. 
-20°C
solubility 
DMF: 25 mg/mL, clear, light yellow
form 
White to off-white solid
BRN 
4289896
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
10
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S7388
Product name
N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide
Packaging
25mg
Price
$97.3
Updated
2024/03/01
Sigma-Aldrich
Product number
573462
Product name
N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide
Packaging
25mg
Price
$82.8
Updated
2024/03/01
Cayman Chemical
Product number
14993
Product name
Suc-AAPF-pNA
Purity
≥95%
Packaging
10mg
Price
$45
Updated
2024/03/01
Cayman Chemical
Product number
14993
Product name
Suc-AAPF-pNA
Purity
≥95%
Packaging
25mg
Price
$78
Updated
2024/03/01
Sigma-Aldrich
Product number
S7388
Product name
N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide
Packaging
100mg
Price
$361
Updated
2024/03/01
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SUC-ALA-ALA-PRO-PHE-PNA Chemical Properties,Usage,Production

Description

Suc-AAPF-pNA is a chromogenic substrate that can be cleaved by cathepsin G (Km = 1.7 mM), subtilisins, chymotrypsin (Km = 60 μM), chymase (Km = 4 mM), and cyclophilin, but not neutrophil elastase. Release of p-nitroanilide is monitored at 405-410 nm. This substrate can be used for inhibitor screening and kinetic analysis.

Uses

N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide has been used as a substrate to determine chymotrypsin activity.

Biochem/physiol Actions

N-succinyl-Ala-Ala-Pro-Phe p-nitroanilide is a substrate for subtilisin and proteases.

SUC-ALA-ALA-PRO-PHE-PNA Preparation Products And Raw materials

Raw materials

Preparation Products

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70967-97-4, SUC-ALA-ALA-PRO-PHE-PNARelated Search:


  • N-Succinyl-Ala-Ala-Pro-Phe 4-nitroanilide
  • succinyl-alanyl-alanyl-prolyl-phenylalanine-4-nitroanilide
  • N-succinyl-alanyl-alanyl-prolyl-phenylanaline nitroanilide
  • N-Succinyl-Ala-Ala-Pro-Phe-pNA, N-Succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide
  • Cathepsin G Substrate I
  • N-SUCCINYL-L-ALANYL-L-ALANYL-L-PROLYL-L-PHENYLALANINE 4-NITROANILIDE
  • N-SUCCINYL-ALA-ALA-PRO-PHE-PNA
  • N-SUCCINYL-ALA-ALA-PRO-PHE P-NITROANILIDE
  • Succinyl-Ala-Ala-Pro-Phe-p-nitroanilide - CAS 70967-97-4 - Calbiochem
  • SAAPNA
  • N-Succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine p-nitroanilide
  • Cathepsin G substrate
  • CATHEPSIN G SUBSTRATE I, COLORIMETRIC
  • SUCCINYL-L-ALANYL-L-ALANYL-L-PROLYL-L-PHENYLALANINE-4-NITROANILIDE
  • SUCCINYL-ALA-ALA-PRO-PHE-P-NITROANILIDE
  • SUC-ALA-ALA-PRO-PHE-PARANITROANILIDE
  • SUC-ALA-ALA-PRO-PHE-PNA
  • SUC-AAPF-PNA
  • SUC-ALA-ALA-PRO-PHE-PNA USP/EP/BP
  • 70967-97-4/107409-54-1
  • N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-phenylalaninamide
  • 70967-97-4
  • C30H36N6O9
  • Chymotrypsin, alpha
  • Enzyme Substrates
  • Enzymes, Inhibitors, and Substrates
  • Substrates
  • Substrates by Enzyme
  • Apoptosis and Cell Cycle
  • Cathepsins and Granzymes
  • Cathepsin G
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Biochemicals and Reagents
  • BioChemical
  • amino